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Making babies without eggs may be possible, say scientists
http://www.ecns.cn/learning-Chinese/2016/09-26/227998.shtml
Sep 26th 2016, 14:29
Learning Chinese
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Making babies without eggs may be possible, say scientists
Scientists say early experiments suggest it may one day be possible to make babies without using eggs.
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They have succeeded in creating healthy baby mice by tricking sperm into believing they were fertilising normal eggs.
ͨ¹ýÆÛƾ«×Ó,ÈÃÆäÈÏΪ×Ô¼ºÊ¹Õý³£ÂÑ×ÓÊܾ«,¿Æѧ¼ÒÃÇÒѾ³É¹¦"Ôì"³öÁ˽¡¿µµÄСÊó.
The findings in Nature Communications, could, in the distant future, mean women can be removed from the baby-making process, say the researchers.
¸ÃÑо¿³É¹û·¢±íÔÚ¡¶×ÔȻͨѶ¡·ÔÓÖ¾ÉÏ.Ñо¿ÕßÖ¸³ö,ʵÑé½á¹û»¹Òâζ×Å,½«À´ÉúÓýº¢×ÓÒ²Ðí²»ÔÙÐèҪŮÐÔ.
For now, the work helps to explain some of the details of fertilisation.
Ä¿Ç°,ÕâÒ»Ñо¿ÓÐÖúÓÚ½âÊÍÊܾ«¹ý³ÌÖеÄһЩϸ½Ú.
End of mum and dad?
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The University of Bath scientists started with an unfertilised egg in their experiments. They used chemicals to trick it into becoming a pseudo-embryo.
°Í˹´óѧµÄ¿Æѧ¼ÒÃÇÔÚʵÑéÖÐʹÓÃÁËһöδÊܾ«µÄÂÑϸ°û.ËûÃÇʹÓû¯Ñ§ÎïÖʽ«Æä"×°ÊÎ"³Éһö¼ÙÅßÌ¥.
These "fake" embryos share much in common with ordinary cells, such as skin cells, in the way they divide and control their DNA.
ÕâЩ"¼Ù"ÅßÌ¥ÓëƤ·ôϸ°ûµÈÕý³£Ï¸°ûÔÚ·ÖÁѺͿØÖÆDNA·½ÃæÓкܶ๲ͬµã.
The researchers reasoned that if injecting sperm into mouse pseudo-embryos could produce healthy babies, then it might one day be possible to achieve a similar result in humans using cells that are not from eggs.
Ñо¿ÕßÒò´ËÈÏΪ,Èç¹ûÏòÀÏÊóµÄ"¼Ù"ÅßÌ¥ÖÐ×¢É侫×ÓÄܹ»ÖÆÔì³ö½¡¿µÐ¡Êó,ÄÇô½«À´Í¨¹ýʹÓ÷ÇÂÑ×Óϸ°ûÒ²¿ÉÄÜÔÚÈËÀàÉúÓýÎÊÌâÉÏÈ¡µÃͬÑù½á¹û.
In the mouse experiments, the odds of achieving a successful pregnancy was one in four.
ÔÚʹÓÃÀÏÊó½øÐеÄʵÑéÖÐ,»³Ôгɹ¦ÂÊΪËÄ·ÖÖ®Ò».
Dr Tony Perry, one of the researchers, told the BBC News website: "This is the first time that anyone has been able to show that anything other than an egg can combine with a sperm in this way to give rise to offspring.
Ñо¿ÕßÖ®Ò»ÍÐÄá-ÅåÀﲩʿÔÚ½ÓÊÜBBCÐÂÎÅÍøÕ¾²É·Ãʱ˵£º"ÂÑ×ÓÒÔÍâµÄϸ°ûÄÜÒÔ´ËÖÖ·½Ê½Ó뾫×Ó½áºÏ,²¢ÇÒÔÐÓý³öÐÂÉúÃü,ÕâÉÐÊôÊ×´Î."
"It overturns nearly 200 years of thinking."
"Ëüµß¸²ÁËÈËÃǽü200ÄêÀ´µÄÈÏʶ."
Those baby mice were healthy, had a normal life expectancy and had healthy pups of their own.
ʵÑéÖе®ÉúµÄÀÏÊóÃǶ¼ºÜ½¡¿µ,ÓÐ×ÅÕý³£µÄÔ¤ÆÚÊÙÃü,²¢ÄÜ·±Ñܽ¡¿µµÄºó´ú.
Ó¢ÎÄÀ´Ô´£ºBBC
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